Genotyping
Genetics play an important role in our health and well-being, and understanding individual genetic variations opens the door to personalised medicine and preventive healthcare interventions.
Our state-of-the-art molecular laboratory offers genotyping analyses that provide in-depth insights into your genetic material. Using advanced technologies and our experienced staff, we can analyse your DNA to identify genetic variations.
Our goal is to provide you with the necessary insight into your genetic profile with the highest degree of accuracy and reliability. We offer genotyping of four key genes: COMT, APOE, TNF-alpha, and MTHFR. These genes are relevant for various aspects of your health, including your cardiovascular and brain function, as well as your immune system and metabolism.
Price: 1.450 DKKANALYSIS METHOD
Using qPCR as our primary analysis method, we can deliver results with precision and sensitivity. This technology enables us to efficiently and accurately identify specific genetic markers.
GENES
Selected genes that are important for your health: APOE, MTHFR, COMT, and TNF-α.
RESULTS
Genetic reports including interpretation information, providing you with an overview of your results, allowing you to easily interpret your genetic variants.
Understand the significance of your genes
APOE
The APOE gene codes for apolipoprotein E, a protein that plays an important role in transporting lipids (fats) in the body. There are three main variants of the APOE gene: E2, E3, and E4. These variants have different impacts on your cholesterol and lipid levels, affecting the risk of certain health conditions.
Analysis of APOE can provide information about your risk of developing cardiovascular diseases and Alzheimer’s disease. This can help guide and initiate preventive measures, including lifestyle changes.
- E2: Having this variant statistically lowers the risk of developing Alzheimer’s and cardiovascular diseases.
- E3: The most common variant and is neutral in terms of disease risk.
- E4: Increases your risk of Alzheimer’s and cardiovascular diseases, and preventive measures should therefore be initiated.
MTHFR
The MTHFR gene codes for the enzyme methylenetetrahydrofolate reductase, which plays a central role in the conversion of vitamin B like folate. Folate is important for DNA synthesis, repair processes, and methylation reactions in the body.
The MTHFR gene can have variations or mutations, the most well-known being C677T and A1298C, which reduce enzyme activity and can lead to the accumulation of the amino acid homocysteine in the blood. Homocysteine, which is normally converted to cysteine and methionine through methylation, requires important B vitamins such as B12, B6, and B9 for this process. Deficiency in these vitamins can disrupt methylation and result in elevated levels of homocysteine, which is linked to various health issues, including cardiovascular diseases and neurological disorders.
- C677T variant: Individuals with this variant may have reduced enzyme activity, leading to the accumulation of homocysteine in the blood, which is associated with an increased risk of certain cardiovascular diseases.
- A1298C variant: This variant can also affect enzyme activity and folate metabolism, but its significance is still under investigation.
Genetic analysis of MTHFR can reveal your risk of elevated homocysteine and thus an increased risk of cardiovascular diseases. Awareness of this risk enables the adjustment of supplements or dietary changes to maintain a healthy homocysteine level.
COMT
The COMT gene, which stands for Catechol-O-Methyltransferase, codes for an enzyme with the same name. This enzyme plays a central role in regulating neurotransmitter activity, including dopamine, noradrenaline (also known as norepinephrine), and epinephrine (adrenaline).
Variations in the COMT gene can explain why certain individuals have an increased risk of developing neurological and psychiatric disorders. Additionally, the gene affects how you experience pain and respond to certain medications.
TNF-α
The TNF-α gene codes for a cytokine of the same name, which plays a crucial role in the body’s immune response and inflammatory processes.
There are several variants of the TNF-alpha gene that can affect your level of TNF-alpha production and thus the risk of inflammatory conditions.
Elevated production of TNF-alpha is associated with autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease.
How It Works
1. Booking
You schedule an appointment for the examination on our website. Here, you can choose the time for sampling that suits you best. We will subsequently provide you with further information.
2. Sampling
Sampling takes place in our clinic in Hellerup. In the clinic, our healthcare professionals will take a blood sample. The turnaround time for this examination is approximately 2 weeks.
3. Results
You will receive a genetic report for each gene, containing information about the genetic findings and a description of what the results could mean for you.
Before undergoing a genetic examination, you should consider whether you want to know your genetic predispositions or not.
To ensure that a genetic examination is the right choice for you, we recommend that you familiarise yourself with what the examination includes and does not include. If, after reading this, you still have unanswered questions, you are always welcome to contact us by email or phone.
The discovery of genetic predispositions can affect both you and your relatives, who may have inherited the same gene variant from previous generations. Therefore, it is a good idea to discuss with your family what it could mean for them.
Before we commence the genetic examination, we will obtain your informed consent. Before giving your consent, we will ensure that you have received information about what the examination entails. We will explain the scope of the test, the techniques used, and any potential risks or limitations of the test.
Understand your genetic variants
Book your Genotyping analysis now
Genetics plays an important role in your health and well-being, and by knowing your genetic variants, you have the opportunity to prevent your potential risk of illness through lifestyle changes and other health measures.
Book now